The heroic Martian Mice Freedom fighters continue to battle forces who seek to destroy them and steal their valuable assets. This time around, it's the evil Catatonians, a cat-like race of creatures who desire the greatest prize on Mars - The Regenerator.
You see, while Mars once had ample supplies of water, those days passed into history when the planet was strip mined by the conquests of the Plutarkians. Today, the Martian Mice are dependent upon the Regenerator to create their water. It is a brilliant machine created by the equally brilliant General Stoker. Without it, it is only a matter of time until all of Martian Mousedom will perish. But the Catatonians have their own problems. With their own planet turned into a used up litter box, they must seek new planets to convert into giant sandboxes so necessary to the life of a cat. With the Regenerator in their paws, the Catatonians would possess the ability to transform any body of land anywhere into a giant litterbox fit to sustain Catatonian life. The fact that the Catatonians are the natural enemies of the Martian Mice is just a bonus.
The Catatonians have succeeded in getting their claws on the Regenerator only to have it destroyed ! But as fate would have it, Stoker created two such Regenerators. The bad news is that the second Regenerator has been stolen by the infamous Chicago based real estate developer, Ronaldo Rump. Rump has used the powerful device to turn the Windy City into a Rump Development and he doesn't intend to stop there. If Rump can acquire enough Regenerator power, he plans to turn Mexico into the largest Rump Golf and Hotel Resort in the World not to mention his desire to melt the Polar Ice Caps to create virgin beach front property! And so as the Biker Mice From Mars return to the city of Chicago, they must not only capture the Regenerator in time to save their planet, the must stop Ronaldo Rump from turning Planet Earth into one large Rump Development while continuing to battle the Catatonians who also seek the Regenerator. So begins the epic journey of the Biker Mice From Mars. They are back riding some of the most awsome motorcycles ever designed! Rev up your engines and get ready to put the pedal to the metal because, once again, it's time to...
ROCK AND RIDE!